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Kayoko Mihara Selected Research

Quinazolinones

6/2004Neuroprotective effects of a novel poly(ADP-ribose) polymerase-1 inhibitor, 2-[3-[4-(4-chlorophenyl)-1-piperazinyl] propyl]-4(3H)-quinazolinone (FR255595), in an in vitro model of cell death and in mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

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Kayoko Mihara Research Topics

Disease

4Parkinson Disease (Parkinson's Disease)
11/2007 - 06/2004
4Stroke (Strokes)
03/2007 - 09/2004
4Thrombosis (Thrombus)
01/2005 - 07/2003
3Neurodegenerative Diseases (Neurodegenerative Disease)
03/2007 - 06/2004
3Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
03/2007 - 03/2004
2Catalepsy
07/2008 - 11/2007
2Brain Ischemia (Cerebral Ischemia)
03/2007 - 01/2005
2Brain Injuries (Brain Injury)
03/2007 - 01/2005
2Ischemic Stroke
01/2005 - 03/2004
1Memory Disorders (Memory Loss)
11/2007
1Cerebral Hemorrhage
11/2005
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
11/2005
1Hemorrhage
11/2005
1Intracranial Aneurysm (Cerebral Aneurysm)
11/2005
1Neurologic Manifestations (Neurological Manifestations)
01/2005
1Thrombotic Stroke
01/2005
1Cerebral Infarction
01/2005
1Brain Infarction
01/2005
1Carotid Artery Thrombosis
07/2003

Drug/Important Bio-Agent (IBA)

5((S)- 2- acetylamino- 3- ((R)- (1- (3- (piperidin- 4- yl)propionyl)piperidin- 3- ylcarbonyl))amino) propionic acid trihydrateIBA
11/2005 - 03/2004
2Adenosine (Adenocard)FDA LinkGeneric
07/2008 - 11/2007
2Adenosine A2A Receptor (Adenosine A2A Receptors)IBA
07/2008 - 11/2007
2Haloperidol (Haldol)FDA LinkGeneric
07/2008 - 11/2007
25- (5- amino- 3- (4- fluorophenyl)pyrazin- 2- yl)- 1- isopropylprydine- 2(1H)- oneIBA
07/2008 - 11/2007
21- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
03/2007 - 06/2004
2Neuroprotective AgentsIBA
09/2004 - 06/2004
1P-2 (P 2)IBA
11/2007
1istradefyllineIBA
11/2007
1Scopolamine (Hyoscine)FDA Link
11/2007
1Adenosine-5'-(N-ethylcarboxamide) (NECA)IBA
11/2007
1Dihydroxyphenylalanine (Dopa)IBA
11/2007
1Dopamine (Intropin)FDA LinkGeneric
11/2007
1Levodopa (L Dopa)FDA LinkGeneric
11/2007
1Cytotoxins (Cytolysins)IBA
03/2007
1PPAR deltaIBA
03/2007
1GW 501516IBA
03/2007
1Acetic Acid (Vinegar)FDA LinkGeneric
03/2007
14- (3- (2- propyl- 3- hydroxy- 4- acetyl)phenoxy)propyloxyphenoxy acetic acidIBA
03/2007
1Collagenases (Collagenase)FDA Link
11/2005
1AnticoagulantsIBA
11/2005
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
11/2005
1Fibrinolytic Agents (Antithrombotic Agents)IBA
11/2005
1Tissue Plasminogen Activator (Alteplase)FDA Link
01/2005
1Platelet Membrane GlycoproteinsIBA
01/2005
1Glycoproteins (Glycoprotein)IBA
09/2004
1Poly(ADP-ribose) Polymerase InhibitorsIBA
09/2004
12- (4- chlorophenyl)- 5- quinoxalinecarboxamideIBA
09/2004
1QuinazolinonesIBA
06/2004
1Pharmaceutical PreparationsIBA
06/2004
12-(3-(4-(4-chlorophenyl)-1-piperazinyl) propyl)-4(3H)-quinazolinoneIBA
06/2004
1Poly (ADP-Ribose) Polymerase-1IBA
06/2004
1ThrombinFDA Link
03/2004
1ThromboxanesIBA
03/2004
1ozagrelIBA
03/2004
1argatroban (MPQA)FDA Link
03/2004
1propionic acid (potassium propionate)IBA
03/2004
1FR 171113IBA
07/2003
1PAR-1 ReceptorIBA
07/2003

Therapy/Procedure

1Intramuscular Injections
07/2008
1Secondary Prevention
03/2004